Legal Male Sex Hormones Avanafil 330784-47-9 Anabolic Pharmaceutical Intermediate

 

Legal Male Sex Hormones Avanafil 330784-47-9 Anabolic Pharmaceutical Intermediate

 

Description:

 

Avanafil is used to treat male sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, avanafil works by increasingblood flow to the penis to help a man get and keep an erection.
This drug does not protect against sexually transmitted diseases (such as HIV,hepatitis B, gonorrhea, syphilis). To decrease your risk of infection, always use an effective barrier method (latex or polyurethane condom/dental dams) during all sexual activity. Consult your doctor or pharmacist for more details.

 

Quick details:

 

Chemical name: Avanafil (Steroids)


Assay: 99% min.


CAS: 330784-47-9


Molecular Formula:C23H26ClN7O3


Molecular Weight:483.9506

Character: White to Off-White Cyrstalline Solid.


Usage: Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.


Categories: Active Pharmaceutical Ingredients; Cnbio; Erectile Dysfunction; Inhibitors; Intermediates &

Fine Chemicals; Pharmaceuticals; API's.

 

COA:

Product name Avanafil
Synonyms 4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide;
(S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidine
CAS No. 330784-47-9
Molecular weight 483.95
Molecular Formula C23H26ClN7O3
Appearance White or off-white crystalline power
Assay >99%(HPLC)
Appearance 2 Years
Solubility Practically insoluble in water and Slightly soluble in ethanol
Melting point 162-165°C
Heavy metals ≤10ppm
Loss on drying ≤0.5%
Sulphated ash ≤0.1%
Other impurities ≤0.5%
Product Categories Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Packaging 1kg/ bag or as client requirment.
Delivery Detail Prompt shipment after receipt of order confirmation.
Storage Avanafil should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.
Usage Avanafil is a PDE5 inhibitor approved for erectile dysfunction.

 

Applications:


Avanafil occurs as white crystalline powder, molecular formula C23H26ClN7O3 and molecular weight of 483.95 and is slightly soluble in ethanol, practically insoluble in water, and soluble in 0.1 mol/L hydrochloric acid. STENDRA, for oral administration, is supplied as oval, pale yellow tablets containing 50 mg, 100 mg, or 200 mg avanafil debossed with dosage strengths. In addition to the active ingredient, avanafil, each tablet contains the following inactive ingredients: mannitol, fumaric acid, hydroxypropylcellulose, low substituted hydroxypropylcellulose, calcium carbonate, magnesium stearate, and ferric oxide yellow.
Avanafil comes as a tablet to take by mouth. It is usually taken with or without food as needed, about 30 minutes before sexual activity. Do not take avanafil more often than once in 24 hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take avanafil exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Your doctor will probably start you on an average dose of avanafil and may increase or decrease your dose depending on how you respond to the medication. Tell your doctor if avanafil is not working well or if you experience side effects.

 

Do NOT use avanafil if:

  • you are allergic to any ingredient in avanafil
  • you have been advised by your doctor to avoid sexual activity
  • you have severe liver or kidney problems, or you are on dialysis
  • you have certain eye problems (eg, a hereditary degenerative retinal disorder, including retinitis pigmentosa)
  • you have certain heart problems (eg, unstable angina, angina during sexual intercourse, severe heart failure), low blood pressure, or uncontrolled high blood pressure
  • you have had a heart attack, stroke, life-threatening irregular heartbeat, or a certain type of heart surgery within the past 6 months

How to use avanafil:

Use avanafil as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with avanafil. Talk to your pharmacist if you have questions about this information.
  • Take avanafil by mouth with or without food.
  • Take avanafil before sexual activity as you were told by your doctor. If you are not sure when to take avanafil, talk with your doctor.
  • Do NOT take more than the recommended dose without checking with your doctor. Do NOT take avanafil more often than 1 time daily.
  • Eating grapefruit or drinking grapefruit juice may increase the amount of avanafil in your blood, which may increase your risk of side effects. Talk with your doctor before including grapefruit or grapefruit juice in your diet.
  • If you miss a dose of avanafil and you still intend to engage in sexual activity, take it as soon as you remember. Continue to take it as directed by your doctor.

Ask your health care provider any questions you may have about how to use avanafil.

 

 

   
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